Samsung looks beyond smartphones to next-gen biologics


The Samsung group diversified into the pharmaceutical sector in 2011. Now, it’s mobilising its expertise in semiconductor making and engineering know-how to make the way biologics are produced on behalf of Big Pharma more efficient. Photo: Bloomberg

The Samsung brand is best known for its smartphones and wide-screen TVs. Yet behind the scenes, the conglomerate is also making a name as a contract manufacturer of complex medicines to treat diseases like cancer.
On a piece of reclaimed land along the western coast of South Korea, Samsung BioLogics Co. is building a $740 million factory that will give it the capacity to become the No. 1 producer by volume of a class of drugs called biologics, many of which are derived from mammal cells.
The Samsung group diversified into the pharmaceutical sector in 2011. Now, it’s mobilising its expertise in semiconductor making and engineering know-how to make the way biologics are produced on behalf of Big Pharma more efficient. The market for biologic medicines, which are used for everything from cancer to arthritis, is projected to exceed $223.7 billion by 2021, according to a Bloomberg Intelligence analysis.
Being a force in biologics is crucial to Samsung — and South Korea. Galaxy smartphones and other consumer electronics face intense competition from Apple and Chinese brands such as Huawei Technologies, and the chaebol is grappling with the arrest of de facto leader Jay Y Lee in a scandal that brought down the country’s former president. Meanwhile, the broader economy needs new industries as shipbuilding and heavy manufacturing slow.
If the past 40 years of global economic growth were fuelled by technology, said Kim Tae-han, chief executive officer of Samsung BioLogics, the next will be fuelled by where that converges with health care.
In an interview at company headquarters in Incheon, Kim said he is preparing to ramp up production and is in negotiations for more than 15 new contracts. The Samsung board gave him the green light and $2 billion to start the business about six years ago. Yet, on the strength of demand and business performance, “I’ve already spent $3 billion!’’ Kim said. Sales totalled 107.6 billion won ($96 million) in the first quarter, a 2.1 per cent increase from a year earlier, though the unit still posted a net loss.
More than 2,000 construction workers — most with experience building semiconductor facilities — are buzzing around the factory site about an hour’s drive from Seoul. It is called Edison and is the company’s third drug facility. Its five floors encompass 34 meters (112 feet), making way for custom-made vats that are so big some shoot through several floors.Samsung, pharmaceutical
Biologic drugs are grown from cells. That necessitates a more complex manufacturing process than typical pills — a mixture of chemicals — but makes biologics more effective and capable of being targeted toward certain diseases.
Building a biologic plant is similar to one for semiconductors. There are clean rooms that cannot tolerate dust or other contamination, so Edison is being built without nuts or bolts to prevent any drilling. As such, everything is welded and tilted to fit together. One day, Kim said, “contract manufacturing” could extend to helping clients build the factories.
“We know how to optimise that process,” Kim said, citing the experience in semiconductors. “We could be competitive in quality, speed and cost.”
Samsung already is a contract manufacturer for some blockbuster drugs, including for Switzerland’s Roche Holding AG and the US’s Bristol-Myers Squibb Co. It will take three years for the plant to ramp up to full capacity after being completed this year and opening at the end of 2018, Kim said.
At its Incheon facilities, staff are on site 24 hours a day to ensure continuity: researchers in white smocks spend the day monitoring the production process, checking on centrifuges or poring over data on computer monitors. English is the working language and some are alums of Genentech Inc. or Amgen Inc., the US-based biotechnology giants. It has 1,700 employees, and their average age is 28, the youngest in the Samsung affiliates.
Globally, the drug industry produces 4 million liters of biologic drugs a year, and that’s projected to double by 2030, Kim said. With its new plant, Samsung BioLogics is positioning itself to double its market share. Shares are up 24 per cent this year to 187,000 won. That compares with a 13 per cent increase in the benchmark Kospi index.
Kim’s company faces some formidable competitors, who are also expanding. Switzerland’s Lonza Group AG and Germany’s Boehringer Ingelheim GmbH have long histories in the biologics contract manufacturing business, and Japan’s Fujifilm Holdings also entered the business.
“We are aware of expansions and further investments in mammalian cell culture capacities by Big Pharma and contract manufacturers worldwide,” Boehringer Ingelheim said in a statement. It’s investing almost $767 million to build a production facility in Vienna that will create about 500 jobs, the company said in an email.
Fujifilm is investing 14 billion yen ($123 million) to accelerate its drug-manufacturing capacity in the US and UK, it said in April. Through subsidiary Fujifilm Diosynth Biotechnologies, it’s targeting revenue of 100 billion yen for the contract development and manufacturing business by March 2024, it said in an email. Lonza declined to comment.

This week in games: Homeworld’s lost expansion returns, 15 minutes of Beyond Good & Evil 2


E3 is over. Time to settle in for the slow summer months, crank the air conditioning, peruse the Steam Summer Sale, and dream of all the games we’ll be playing in a few months. Mostly Wolfenstein II, I think.

And if you need proof the summer’s slow? Look no further than our news wrap-up this week. We’ve got a few additional trailers for games we saw last week (XCOM 2Total Warhammer IIBeyond Good & Evil), plus a look at the Vive’s finger-tracking controllers and—oh yeah, Homeworld: Cataclysm is finally back on-sale thanks to good and evil 2 resized

This is gaming news for June 19 to 23.

Repeat offender

EA really wants you to own a copy of Medal of Honor: Pacific Assault. It was one of Origin’s “On the House” games in 2016 and now is reprising the same role middle of 2017—which is to say, if you somehow missed it last year you can head to Origin and grab a free copy of Medal of Honor: Pacific Assault.

Chosen one

One of the games we’ll be playing in a few months is XCOM 2: War of the Chosen, which was revealed during the PC Gaming Show last week. And who are “The Chosen”? You can get a glimpse of the first, The Assassin, in the trailer below:


Lizardmen are real

Total War: Warhammer II gave E3 attendees a glimpse of its campaign map last week, and now you sitting at home can get the same glimpse courtesy of this new trailer. The first Total Warhammer’s map was nice enough, but I think it’s outdone by the massive tornado whirling at the center of this one. And don’t forget—those who own both games can supposedly link the campaign maps together into one huge campaign. Still looking forward to that.


Plastic knuckles

We got a glimpse of Valve’s finger-tracking answer to the Oculus Touch controllers during Steam Dev Days last fall, but not much since. I thought we’d see more at GDC, then maybe at E3, but so far nothing.

Units are shipping to developers this week though, and that’s led Valve to post some setup instructions and interesting diagrams online. Maybe we’ll see these controllers by the end of the year? Maybe?

HTC Vive - Knuckles controller


The thawing throne

Blizzard’s StarCraft remaster isn’t even out yet, but the company’s apparently going to keep the nostalgia flowing. As spotted by Blizzplanet (via PC Gamer), a recent job listing for a software engineer at Blizzard mentioned StarCraftWarcraft III, and Diablo II by name, and then went on to say “We’re restoring them to glory, and we need your engineering talents, your passion, and your ability to get tough jobs done.”

Gamescom? BlizzCon? I bet we hear more at one of those.